Detalhe da pesquisa
1.
Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis.
Nature
; 560(7717): 192-197, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30046105
2.
Author Correction: Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis.
Nature
; 619(7970): E48, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37402863
3.
Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition.
Proc Natl Acad Sci U S A
; 116(19): 9318-9323, 2019 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30962368
4.
Ligand binding: evaluating the contribution of the water molecules network using the Fragment Molecular Orbital method.
J Comput Aided Mol Des
; 35(10): 1025-1036, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34458939
5.
A novel multiple-stage antimalarial agent that inhibits protein synthesis.
Nature
; 522(7556): 315-20, 2015 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26085270
6.
Inhibition of CorA-Dependent Magnesium Homeostasis Is Cidal in Mycobacterium tuberculosis.
Antimicrob Agents Chemother
; 63(10)2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31383669
7.
Diversity-oriented synthesis of bicyclic fragments containing privileged azines.
Bioorg Med Chem Lett
; 29(2): 248-251, 2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30501964
8.
Generation of Polar Semi-Saturated Bicyclic Pyrazoles for Fragment-Based Drug-Discovery Campaigns.
Chemistry
; 24(41): 10443-10451, 2018 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29732638
9.
2,4-Diamino-6-methylpyrimidines for the potential treatment of Chagas' disease.
Bioorg Med Chem Lett
; 28(18): 3025-3030, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30104093
10.
Drug discovery for male subfertility using high-throughput screening: a new approach to an unsolved problem.
Hum Reprod
; 32(5): 974-984, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28333338
11.
Screening a protein kinase inhibitor library against Plasmodium falciparum.
Malar J
; 16(1): 446, 2017 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29115999
12.
Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis.
Nature
; 537(7618): 122, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27281209
13.
N-myristoyltransferase inhibitors as new leads to treat sleeping sickness.
Nature
; 464(7289): 728-32, 2010 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20360736
14.
Respiratory flexibility in response to inhibition of cytochrome C oxidase in Mycobacterium tuberculosis.
Antimicrob Agents Chemother
; 58(11): 6962-5, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25155596
15.
Clinically relevant enhancement of human sperm motility using compounds with reported phosphodiesterase inhibitor activity.
Hum Reprod
; 29(10): 2123-35, 2014 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25124668
16.
Application of an NMR/Crystallography Fragment Screening Platform for the Assessment and Rapid Discovery of New HIV-CA Binding Fragments.
ChemMedChem
; : e202400025, 2024 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38581280
17.
Correction: Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies.
PLoS One
; 19(4): e0302418, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38626090
18.
Comparison of a high-throughput high-content intracellular Leishmania donovani assay with an axenic amastigote assay.
Antimicrob Agents Chemother
; 57(7): 2913-22, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23571538
19.
Correction to "Bespoke Drug Discovery Training for Low-Middle Income Countries".
ACS Med Chem Lett
; 14(11): 1602, 2023 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37970589
20.
Design of the Global Health chemical diversity library v2 for screening against infectious diseases.
PLoS Negl Trop Dis
; 17(12): e0011799, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38150490